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Ingredient source facts

Fluorescein, 2',4',5',7'-tetrabromo-4,5,6,7- tetrachloro-, disodium salt (CI 45410): EU cosmetic annex conditions and formula evidence

Fluorescein, 2',4',5',7'-tetrabromo-4,5,6,7- tetrachloro-, disodium salt (CI 45410) has identifier matches to Annex III in the acquired 18 May 2026 EU Cosmetics Regulation text. The table distinguishes the substance identity, product-use conditions and recorded limits. Confirm the exact substance/group scope, formula concentration and intended use before applying an entry. This does not certify formula safety or settle Great Britain requirements.

Evidence retrieved 2026-10-06. Source versions and topic-specific limits are listed below.

Exact legal-entry matches and product-use conditions

Exact checksum-valid CAS and/or exact EC identifier in preserved legal identity cells. Group and substance scope are still conditional.

Each line below retains its own concentration basis, conditions and warnings. Blank source cells mean no condition was recorded in that cell; they do not establish unrestricted use.

Annex III · Entry 270

Recorded identity: Fluorescein, 2',4',5',7'-tetrabromo-4,5,6,7-tetrachloro-, disodium salt (CI 45410)

Matching CAS: 18472-87-2 · Matching EC: 242-355-6

Product use / body siteMaximum concentration and basisOther conditionsWarningsSource
(a) Hair dye substance in oxidative hair dye productsBlank in source(a) After mixing under oxidative conditions the maximum concentration applied to hair must not exceed 2,0 %(a) To be printed on the label: The mixing ratio. ‘ Hair colorants can cause severe allergic reactions. Read and follow instructions. This product is not intended for use on persons under the age of 16. Temporary “black henna” tattoos may increase your risk of allergy. Do not colour your hair if: — you have a rash on your face or sensitive, irritated and damaged scalp, — you have ever experienced any reaction after colouring your hair, — you have experienced a reaction to a temporary “black henna” tattoo in the past.’[2]
(b) Hair dye substance in non-oxidative hair dye products(b) 0,4 %Blank in sourceBlank in source[2] [3]

The consolidated text is a dated reference. Current amendments, corrigenda and applicability dates must be checked. EU evidence does not resolve Great Britain rules.

Known facts and deciding inputs

Known context: EU. Ingredient identity is recorded; concentration, intended use, exposure and current legal conditions still need checking.

Source factRecorded valueWhat to check
INCI / recorded nameFluorescein, 2',4',5',7'-tetrabromo-4,5,6,7- tetrachloro-, disodium salt (CI 45410) [1]Check identity, concentration, exposure and use against the current legal annex and any amendments.
Common ingredients glossary nameACID RED 92 [1]Check identity, concentration, exposure and use against the current legal annex and any amendments.
CAS identifiers18472-87-2 [1]Check identity, concentration, exposure and use against the current legal annex and any amendments.
EC identifiers242-355-6 [1]Check identity, concentration, exposure and use against the current legal annex and any amendments.
Informative CosIng functionsCOLORANT [1]Check identity, concentration, exposure and use against the current legal annex and any amendments.
Chemical nameFluorescein, 2',4',5',7'-tetrabromo-4,5,6,7- tetrachloro-, disodium salt (CI 45410) [1]Check identity, concentration, exposure and use against the current legal annex and any amendments.
CosIng annex referenceIII [1]Check identity, concentration, exposure and use against the current legal annex and any amendments.
CosIng reference entry270 [1]Check identity, concentration, exposure and use against the current legal annex and any amendments.
maximumConcentration(b) 0,4 % [1]Check identity, concentration, exposure and use against the current legal annex and any amendments.
wordingOfConditions(a) To be printed on the label: The mixing ratio. “ Hair colorants can cause severe allergic reactions. Read and follow instructions. This product is not intended for use on persons under the age of 16. Temporary ‘black henna’ tattoos may increase your risk of allergy. Do not colour your hair if: — you have a rash on your face or sensitive, irritated and damaged scalp, — you have ever experienced any reaction after colouring your hair, — you have experienced a reaction to a temporary ‘black henna’ tattoo in the past.” [1]Check identity, concentration, exposure and use against the current legal annex and any amendments.
productTypeBodyParts(a) Hair dye substance in oxidative hair dye products (b) Hair dye substance in non-oxidative hair dye products [1]Check identity, concentration, exposure and use against the current legal annex and any amendments.
other(a) After mixing under oxidative conditions the maximum concentration applied to hair must not exceed 2,0 % [1]Check identity, concentration, exposure and use against the current legal annex and any amendments.
SCCS opinion referenceOpinion on Acid Red 92, Opinion on Acid Red 92 [1]Check identity, concentration, exposure and use against the current legal annex and any amendments.
Related regulation reference(EC) 2013/1197 [1]Check identity, concentration, exposure and use against the current legal annex and any amendments.
Recorded publication date2013-11-25T00:00:00.000+0100 [1]Check identity, concentration, exposure and use against the current legal annex and any amendments.

Resolve the entry against your actual formula

Use this checklist to gather your business or product details before speaking with a specialist. The items below explain what to record and suggest useful supporting documents. You can add your own answers in the editable project brief.

  1. Does the supplied material fall within these exact entries?

    Put your supplier CAS/EC, substance composition, salt/group membership, purity, physical form and intended function beside each matched entry. A matching identifier does not resolve every group or impurity condition.

    Useful evidence: Supplier specification, composition and certificates of analysis; the exact annex rows above.

  2. Which row governs the finished-product use?

    Compare the finished-product concentration, body site, rinse-off/leave-on use, consumer/professional setting and any exposure restrictions with each row. Preserve the units and calculation basis; do not transfer a limit from a different product-use row.

    Useful evidence: Quantitative formula and use instructions; a row-by-row condition and warning worksheet.

  3. Is a prohibition or trace question involved?

    For Annex II matches, review Article 14 before formulation decisions. Article 17 concerns a separate, conditional non-intended trace situation; it does not grant blanket permission to intentionally add a prohibited substance. Record origin and technical-avoidability evidence for specialist review.

    Useful evidence: Ingredient/impurity origin, manufacturing controls, trace quantities and the cited Article 17 text.

  4. What must reach the safety assessor and Responsible Person?

    Send the reconciled identity, condition table, exposure facts, supplier evidence and unresolved amendment/date questions. Agree formula, assessment and PIF responsibilities before notification or manufacturing handoff.

    Useful evidence: A dated formula-evidence matrix, supplier data, exposure description and document ownership list.

Work packages and dependencies

What needs to happen first

Questions for providers

Sources and data dates

Read the official document in context. The audit details identify the precise locators and preserved versions used for this page.

EUR-Lex — Regulation (EU) 2009/1223 ↗

Consolidated text dated 2026-05-18 · retrieved 2026-10-06

Audit details: precise locators and snapshot identifiers

Source key D05 · snapshot fc7ca1c1b06e5052fbfd81afd57c8ba69d4c215a4fc4a2a8385b9bff94a7b591

  • [2] HTML table[2] in substantive document container (extraction legal-html-tables-2) / own tr[500] · record 86fb4c16f9f8ecc3605f02255d03f01c50ca2f393ef1423a545305680a3ee783
  • [3] HTML table[2] in substantive document container (extraction legal-html-tables-2) / own tr[501] · record 5bed71e1643f3b67c2dd01a70e3521b7e22e8cd101776bd2251cfd0f8057938c
  • [4] #art_14 · record 9ffeb5c563a32fe8d532de5d352c05f8a9062e1c5d21fd326d5e6c2ea42a84f4
  • [5] #art_17 · record 8ad3194ae1fc45e70495aa637f90457139a0023680e2b880fc4c8a8b4d202c43
  • [6] #art_10 · record 49eb173406b736d6f0b855572abc53b0f52d9543a4d170affa8ae68d6e809718
  • [7] #art_11 · record ba70c2a84c1d6c70eb57a0fd892fcdf584f6142281b03c29be4bd20e6e83844d

Prepare an editable project brief

Confirm the facts, scope and contact preference before sharing your project. Preparing this page sends no provider outreach.

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