Published: December 2025 | Category: 510(k) Consulting

How to Combine 510k Consultants with AI Tools Like Cruxi

You don't have to choose between a 510k consultant and AI-powered software. The best approach combines both: AI handles structured drafting and evidence mapping, while consultants focus on strategy and FDA interactions. Here's how to make it work.

The Hybrid Model: Best of Both Worlds

The hybrid approach leverages AI for efficiency and consultants for expertise:

AI Tools Handle:

  • Structured drafting of submission sections
  • Evidence mapping and organization
  • Consistency checks and formatting
  • RTA prevention (completeness checks)
  • Content reuse across submissions

Consultants Focus On:

  • Regulatory strategy and classification
  • Predicate selection and justification
  • FDA communications and negotiations
  • High-level review and quality assurance
  • Complex problem-solving

Cost Savings: 60-80% Reduction

Traditional consultant-only model: $30k–$80k+ for full-service 510(k) preparation

Hybrid AI + consultant model: $5k–$20k in service fees

Why the savings? Consultants spend less time on manual drafting and more time on high-value strategy. AI tools handle the repetitive, structured work that would otherwise take consultants 30-50 hours.

Example: A consultant typically charges $250/hour. If AI saves 40 hours of drafting time, that's $10,000 in savings—while maintaining or improving quality through structured workflows.

Faster Preparation: 2-4 Months vs 3-6 Months

Structured workflows accelerate preparation:

  • AI drafts sections in parallel while consultants review and provide strategic input
  • Consistent formatting reduces back-and-forth revisions
  • Evidence mapping ensures nothing is missed
  • RTA prevention catches issues before submission

Traditional model: Consultant writes from scratch, client reviews, multiple revision cycles. Hybrid model: AI structures content, consultant reviews and enhances, faster iteration.

How It Works in Practice

Step 1: AI Structures the Submission

You enter your device information into the AI platform (e.g., Cruxi). The system:

  • Identifies device classification and regulation number
  • Suggests and scores potential predicate devices
  • Maps evidence requirements across all eSTAR sections
  • Drafts submission sections with traceable source citations
  • Generates a complete evidence checklist

Step 2: Consultant Reviews and Enhances

Your consultant receives a well-organized, structured draft. They:

  • Review the classification and predicate selection
  • Enhance the regulatory strategy
  • Refine the substantial equivalence comparison
  • Ensure all FDA guidance is properly addressed
  • Prepare for FDA communications

Step 3: Collaborative Refinement

You and your consultant work together to:

  • Review and refine the AI-drafted content
  • Add device-specific details and technical depth
  • Ensure consistency across all sections
  • Finalize the submission package

When the Hybrid Model Works Best

  • Startups and small teams: Need cost efficiency without sacrificing quality
  • Standard Class II devices: Clear regulatory pathways benefit from structured workflows
  • Teams with some internal RA capacity: Can handle basic review, need consultant for strategy
  • Multiple submissions: Content reuse across devices saves significant time
  • RTA prevention focus: Structured workflows catch common mistakes

When You Might Need Full Consultant Service

The hybrid model may not be ideal for:

  • Novel or borderline De Novo devices: Require extensive regulatory strategy
  • Very complex software (SaMD): Need deep cybersecurity and IEC 62304 expertise
  • High-risk devices: Require extensive clinical strategy
  • Teams with zero internal RA capacity: Need more hand-holding

Even in these cases, AI tools can still help with drafting and organization—the consultant just spends more time on strategy.

How to Engage a Consultant for Hybrid Work

When scoping a consultant for hybrid work, be clear about:

  • What AI will handle: Structured drafting, evidence mapping, initial content generation
  • What consultant will handle: Strategy, review, FDA communications, quality assurance
  • Deliverables: Consultant provides review comments, strategic input, and FDA management—not full drafting
  • Pricing: Should reflect reduced scope (review vs. drafting)

Example SOW clause: "Consultant will review AI-drafted 510(k) sections, provide strategic enhancements, manage FDA communications, and ensure regulatory compliance. Consultant is not responsible for initial drafting, which will be handled by the client using AI-powered tools."

Real-World Example

Traditional approach: A startup hires a consultant for $60k to draft a full 510(k). Takes 5 months. Consultant spends 200 hours on drafting and 50 hours on strategy.

Hybrid approach: Same startup uses Cruxi to structure and draft the submission ($5k), then hires a consultant for review and strategy ($15k). Takes 3 months. Consultant spends 20 hours on review and 40 hours on strategy—more time on high-value work.

Result: $40k savings, 2 months faster, higher quality through structured workflows.

Ready to Try the Hybrid Approach?

Our comprehensive 510k Consultant Engagement Guide includes:

  • How to scope consultant work for hybrid projects
  • Sample SOW clauses for AI+consultant engagements
  • Pricing strategies for hybrid models
  • Tips for finding consultants open to hybrid work

Download the Free 40-Page Guide →

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